Derek LeRoith
National Institutes of Health
Bethesda, Maryland, U.S.A.

Walter Zumkeller
Universitaet Halle

Robert C. Baxter
University of Sydney

Table of Contents

IGF-I gene and protein structure and function
Martin Adamo

The Many Levels of Control of IGF-II Expression
P. Elly Holthuizen

IGF and imprinting
Schofield

Structure and Function of the IGF-1 and Mannose 6-Phosphate/IGF-2 Receptors
Susan L. Spence and Peter Nissley

The Structure of the Type 1 Insulin-Like Growth Factor Receptor
Colin W. Ward, Thomas P.J. Garrett, Mei Lou, Neil M McKern, Timothy E. Adams, Thomas C. Elleman, Peter A. Hoyne, Maurice J. Frenkel, Leah J. Cosgrove, George O. Lovrecz, Lindsay G. Sparrow, Lynne Lawrence and V. Chandana Epa

IGFBPs
Matt Rechler

IGFs and the CNS
Eva Feldman

IGFs and the mammary gland
Terry Wood

IGFs and the GI tract
Kay Lund

IGFs and the heart
Ross Clarke

IGFs and the immune system

IGFs and development
David Hill

IGFs and bone
Cliff Rosen

IGFs and muscle
Peter Rotwein

IGFs and the kidney
Ralph Rabkin

IGFs and the reproductive system
Adashi

IGFs and nutrition
Denise Ney section 3 cancer

IGFs and cancer epidemiology
Hankinson

IGFBP-3
Michael Pollak

IGFs and prostate cancer
Steve Plymate

IGFs and breast cancer
Janet Martin

Insulin and IGF-I receptors in cancer

The Molecular Basis of IGF-I Receptor Gene Expression in Human Cancer
Haim Werner

IGFs and sarcomas
Lee Helman

IGF-I Receptor Signaling in Health and Disease
Renato Baserga, Marco Prisco and Tina Yuan

IGFs and epithelial cancers
Walter Zumkeller

Insulin-Like Growth Factors and Hematological Malignancies
Anne J. Novak and Diane F. Jelinek

IGFBPs and IGF-independent effects
Youngman Oh

IGFBPs and BP-1 migration/trophoblast
Linda Giudice

IGFBP3/RXR
Pinchas Cohen

IGFBP-5/bone
S. Mohan

IGFBP-5/matrix
David Clemmons

IGFBPs and TGF-beta
Robert Baxter

Insulin-Like Growth Factor Binding Proteins (IGFBPs) and Apoptosis
C.M. Perks and J.M.P. Holly

Clinical applications of IGFs
Nelly Maurus

IGFs and NICTH
Naomi Hizuka

IGFs and diabetes
David Dunger

IGFs and critical illness
Van den Bergh

IGFs and Growth
Ron Rosenfeld

Mutations of IGF-I
Cecilia Camacho-Hubner

IGF-I receptor mutations
Steve Chernesauk

BP proteases
Peter Bang

Antisense and Triple Helix Strategies in Basic and Clinical Research: Challenge for Gene Therapy of Tumors Expressing IGF-I L.C.
Upegui-Gonzalez, J.C. Francois, L.A.Trojan, A. Ly, R. Przewlocki, C. Malvy and J. Trojan

IGF Endo versus para/autocrine (debate)
Andrew Butler