Aβ Metabolism and Alzheimer's Disease


Takaomi Saido
RIKEN Brain Science Institute

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ISBN: 978-1-58706-230-8
Pub Date: February 18, 2003
Pages: 179

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Table of Contents

Beta-secretase
M. Citron

Alpha-secretases
S. Ishiura

ADAM 10/alpha secretase and presenilins/gamma secretase in APP processing and notch signaling
D. Hartmann

Gamma-secretase and presenilin
M. Wolfe

Biochemistry of gamma-secretase (tentative title)
S. Sinha

Presenilin and intracellular protein transport

Degradation of Abeta by neprilysin
T.C. Saido

Degradation of Abeta by endothelin-converting enzyme
C. Eckman

Degradation of Abeta by insulin-degrading enzyme

Lipid raft and Abeta metabolism
T. Golde

Lipid raft and Abeta accumulation
M. Morishima-Kawashima and Y. Ihara

Transport-dependent clearance of Abeta
B. Zlokovic

Abeta vaccination
C. Lemere


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