Ronald W. Ellis
Shire Biologics, Inc.

About this Book

This book systematically addresses all the major available direct and enabling technologies which have contributed to the revolutionized research and development, thus improvements to existing vaccines. Its target audience is both research and development workers in the field, as well as health-care personnel who use vaccines. It should serve as an invaluable source-book in the vaccine field.

Table of Contents

New Technologies for Making Vaccines
Ronald W. Ellis

Clinical Issues for New Technologies
Luc Hessel

Regulatory Issues
Marion F. Gruber, Paul G. Richman and Julianne C. M. Clifford

In-Licensing Issues and Vaccine Technologies
Dale R. Spriggs

Live Vaccines
Alan R. Shaw

Recombinant Live Attenuated Viral Vaccines
Richard R. Spaete

Live Viral Vectors
Elizabeth B. Kauffman, Michel Bublot, Russell R. Gettig, Keith J. Limbach, Steven E Pincus and Jill Taylor

Inactivated Virus Vaccines
Andrew D. Murdin, Benjamin Rovinski, Suryaprakash

Live Attenuated Bacterial Vaccines
Kevin P. Killeen and Victor J DiRita

Live Attenuated Bacterial Vectors
Sims K. Kochi and Kevin P. Killeen

Protein-based Vaccines
Sheena M. Loosmore, Gavin R. Zealey and Raafat E.F. Fahim

Peptide Vaccines
Damu Yang, Gregory E. Holt, Michael P. Rudolf, Markwin P. Velders, Remco M. P. Brandt, Eugene D. Kwon and W. Martin Kast

Polysaccharide Vaccines
Stephen Freese

DNA Vaccines
Daniel E. McCallus, Catherine J. Pachuk, Shaw-guang Lee and C. Satishchandran

Plant-Derived Vaccines
Amanda M. Walmsely and Charles J. Arntzen

Biological Aspects and Prospects for Adjuvants and Delivery Systems
Bror Morein and Ke-Fei Hu

Transcutaneous Immunization
Gregory M. Glenn