Quasispecies and RNA Virus Evolution: Principles and Consequences
Esteban Domingo
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ISBN: 978-1-58706-077-9
Pub Date: December 1, 2000
Pages: 221
Figures: 44
Tables: 15
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This book focuses on a new aspect of RNA virology: the highly dynamic, heterogeneous and plastic nature of RNA viruses which comprise more than 75% of the viruses that have been recognized as disease agents. It is the first attempt to bridge the gap from the basic, theoretical formulations underlying error-prone replications and generation of quasispecies, to their impact on how RNA viruses adapt and cause disease.
Table of Contents
Introduction
Multiplication Strategies of RNA Genetic Elements
Molecular Recognition and Replication Enzymes
Quantitative Molecular
Darwinian Evolution of RNA in Vitro
Experimental Studies on Viral Quasispecies
Population Dynamics and Virus Adaptability
Connections, Implications and Prospects
