Xuewu Zhang
South China University of Technology

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About this Book

The early detection of human cancer is still one of the great challenges in the battle against this disease. Single biomarkers are not likely to provide sufficient diagnostic power and multibiomarker assays should be developed in order to reach high diagnostic accuracy for cancer screening at the population level. Omics technologies are emerging new biomarker discovery tools and have a high potential to yield panels of novel and cancer-specific biomarkers. This book provides an overview of recent studies aimed at the discovery of new cancer biomarkers through omics-based approaches, including genomics, transcriptomics, proteomics, metabonomics, peptidomics, phosphoproteomics, immunomics, glycoproteomics, lipidomics, bioinformatics and integrative omics technologies. The book serves as an introduction to researchers in the field and provides the platforms to facilitate the development of new approaches in cancer research.

Table of Contents

1. Genomics in Cancer Biomarker Discovery
Gu Chen, Xuewu Zhang and Shang‑Tian Yang

2. Transcriptomics in Cancer Biomarker Discovery
Jiaying Lin

3. Proteomics in Cancer Biomarker Discovery
Feng Ge and Qing‑Yu He

4. Metabonomics in Cancer Biomarker Discovery
Xuewu Zhang, Gu Chen and Kaijun Xiao

5. Peptidomics in Cancer Biomarker Discovery
Lei Shi

6. Phosphoproteomics in Cancer Biomarker Discovery
Li‑Rong Yu, Yuan Gao and Donna L. Mendrick

7. Usefulness of Immunomics in Cancer Biomarker Discovery
Julie Hardouin and Michel Caron

8. Glycoproteomics in Cancer Biomarker Discovery
Byung‑Gyu Kim and Je‑Yoel Cho

9. Lipidomics in Cancer Biomarker Discovery
Xiaoqiong Ma and Jun Yang

10. Bioinformatics in Cancer Biomarker Discovery
Yee Leng Yap and Xuewu Zhang

11. Integrative Omics Technologies in Cancer Biomarker Discovery
Xuewu Zhang, Lei Shi, Gu Chen and Yee Leng Yap