Robin Hui Liu
Osmetech Molecular Diagnostics

Abraham P. Lee
University of California at Irvine

About this Book

The objective of this book is to provide up-to-date coverage of some of the emerging developments in the field of integrated DNA biochips. It will prove a useful source of information for researchers in the this field and for those who are just entering the field of biochip research.

Table of Contents

1. Integrated DNA Biochips: Past, Present and Future
Piotr Grodzinski, Robin Hui Liu and Abraham P. Lee

2. Integrated Molecular Analyses of Biological Samples on a Bead-Based
Microarray Platform
Joanne M. Yeakley, Daniel A. Peiffer, Marina Bibikova, Tim McDaniel, Kevin L. Gunderson,
Richard Shen, Bahram G. Kermani, Lixin Zhou, Eugene Chudin, Shawn C. Baker,
Kenneth M. Kuhn, Frank Steemers, Mark Hansen, Michael Graige, Celeste McBride,
Steven Barnard, Bob Kain, David Barker and Jian-Bing Fan

3. Integrated Microfluidic CustomArray™ Biochips for Gene Expression
and Genotyping Analysis
Robin Hui Liu, Mike Lodes, H. Sho Fuji, David Danley and Andrew McShea

4. Self-Contained, Fully Integrated Biochip for Sample Preparation, PCR
Amplification and DNA Microarray Analysis
Robin Hui Liu, Piotr Grodzinski, Jianing Yang and Ralf Lenigk

5. Integrating Sample Processing and Detection with Microchip Capillary
Electrophoresis of DNA
Adam T. Woolley

6. Integrated Plastic Microfluidic Devices for Bacterial Detection
Z. Hugh Fan and Antonio J. Ricco

7. PCR in Integrated Microfluidic Systems
Victor M. Ugaz

8. Integrated Nucleic Acid Analysis in Parallel Matrix Architecture
Jong Wook Hong

9. Chip-Based Genotyping by Mass Spectrometry
Kai Tang

10. Analyzing DNA-protein interactions on a chip
Limin Lin and James P. Brody

11. Single Molecule DNA Detection
Tza‑Huei Wang, Christopher M. Puleo and Hsin-Chih Yeh

12. Nanochannels for Genomic DNA Analysis: The Long and the Short of It
Robert Riehn, Walter Reisner, Jonas O. Tegenfeldt, Yan Mei Wang, Chih-kuan Tung,
Shuang-Fang Lim, Edward Cox, James C. Sturm, Keith Morton, Steven Y. Chou
and Robert H. Austin

13. Beyond Microtechnology–Nanotechnology in Molecular Diagnosis
Paolo Fortina, Joseph Wang, Saul Surrey, Jason Y. Park and Larry J. Kricka