Polyploidization and Cancer

Randy Y.C. Poon
Hong Kong University of Science and Technology; Hong Kong

This book will be published on April 1, 2010.
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This book is co-published with Springer.
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ISBN: 978-1-4419-6198-3
Pub Date: April 1, 2010

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Table of Contents

1. Polyploidy, Aneuploidy and the Evolution of Cancer
Lauren M. F. Merlo, Li‑san Wang, John W. Pepper, Peter S. Rabinovitch and Carlo C. Maley

2. Molecular Mechanisms and Function of the Spindle Checkpoint, a Guardian of the Chromosome Stability
Daisuke Ito and Tomohiro Matsumoto

3. Understanding Cytokinesis Failure
Guillaume Normand and Randall W. King

4. DNA Damage and Polyploidization
Jeremy P.H. Chow and Randy Y.C. Poon

5. Role of the p53 Family in Stabilizing the Genome and Preventing Polyploidization
Flaminia Talos and Ute M. Moll

6. Centrosomes, Polyploidy and Cancer
Anette Duensing and Stefan Duensing

7. Polyploidy: Mechanisms and Cancer Promotion in Hematopoietic and Other Cells
Hao G. Nguyen and Katya Ravid

8. Polyploidization of Liver Cells
Séverine Celton‑Morizur and Chantal Desdouets

9. Analysis of Cellular DNA Content by Flow and Laser Scanning Cytometry
Zbigniew Darzynkiewicz, H. Dorota Halicka and Hong Zhao

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