Email this

Print this

G. Chinnadurai
Institute for Molecular Virology, Saint Louis University Health Sciences Center

About this book

This book is a comprehensive monograph on the CtBP family proteins. These proteins
are gaining wide scientific interest due to their critical roles in animal development and in oncogenesis. The CtBP family proteins are multifunctional. They predominantly function as transcriptional corepressors in the nucleus by recruiting various histone modifying enzymes such as histone deacetylases, histone methylases and a histone demethylase. They also perform several diverse cytosolic functions such as Golgi maintenance and in central nervous system synapses.

Table of contents

1. CtBP Family Proteins: Unique Transcriptional Regulators in the Nucleus
with Diverse Cytosolic Functions
G. Chinnadurai

2. Transcriptional Repression by the CtBP Corepressor in Drosophila
Hitoshi Aihara, Lorena Perrone and Yutaka Nibu

3. CtBP and Hematopoietic Transcriptional Regulators
Alexis Verger, Jose Perdomo and Merlin Crossley

4. CtBP: A Link between Apoptosis and the Epithelial-Mesenchymal Transition
Steven M. Frisch

5. The Significance of the CtBP — AdE1A Interaction during Viral Infection
and Transformation
Roger J.A. Grand, Claire Baker, Paola M. Barral, Rachel K. Bruton, Julian Parkhill,
Tadge Szestak and Philip H. Gallimore

6. CtBP Proteins in Vertebrate Development
Jeffrey D. Hildebrand

7. CtBP as a Redox Sensor in Transcriptional Repression
Qinghong Zhang, Clark C. Fjeld, Amanda C. Nottke and Richard H. Goodman

8. CtBP Corepressor Complex–A Multi-Enzyme Machinery that Coordinates
Chromatin Modifications
Yu-Jiang Shi and Yang Shi

9. Structural Determinants of CtBP Function
James R. Lundblad

10. CtBP3/BARS and Membrane Fission
Stefania Spanò, Cristina Hidalgo Carcedo and Daniela Corda

11. CtBPs as Synaptic Proteins
Susanne tom Dieck, Frank Schmitz and Johann Helmut Brandstätter

12. A New Member of the CtBP/BARS Family from Plants: Angustifolia
Hirokazu Tsukaya