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The B7-CD28 Family Molecules


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Lieping Chen
Mayo Clinic


ISBN: 978-0-306-47842-0
Pub date: 2003-10-08
154 pages


Table of contents

Structure prediction and binding site identification of the CD28 and B7 family molecules
Jurgen Bajorath

T-lymphocyte signaling apthways regulated by CD28 and CTLA-4
David J. McKean and Matthew D. Griffin

Costimulatory molecules in T cell development, activation and effector function: similar activity but opposite consequences
Yang Liu, Jian Xin Gao, Xue-Feng Bai, Xingluo Liu, Huiming Zhang and Pan Zheng

Negative costimulatory ligand B7-H1
Haidong Dong, Hideto Tamura, Sheng-Dian Wang and Lieping Chen

PD-1:PD-1 ligand pathway
Gordon Freeman and Arlene Sharpe

The ICOS/B7RP-1 costimulation pathway
Steven K. Yoshinaga

Role of ICOS in T-cell activation
Jeffrey A. Ledbetter, Erik Espling and Marthe Hayden Ledbetter

B7-H3
Andrei I. Chapoval and Lieping Chen

The role of B7s in transplantation
Didier A. Mandelbrot, Wayne R. Godfrey, Arlene Sharpe and Bruze R. Blazar

B7 family molecules in the induction and regulation of autoimmunity
Claudia Jabs, Arlene Sharpe and Vijay Kuchroo

Operation during costimulation: modulation of B7 receptors to elicit anti-tumor immunity
Eugene D. Kwon, Qingyong Ji and Arthur A. Hurwitz