Gian Franco Baronzio
Policinico di Monza

Erich Dieter Hager
Biomed Klinic Germany

About this Book

Following an introductory overview, Hyperthermia In Cancer Treatment: A Primer comprehensively describes the biological reasons for associating hyperthermia with radiation and chemotherapy and the biological and clinical effects of hyperthermia on cancerous and normal tissues. The volume’s 20 chapters are arranged in three principal parts: physical and methodological studies, biologic principles, and clinical studies.

Table of Contents

SECTION I: PHYSICAL ASPECTS OF HYPERTHERMIA

1. Hyperthermia, Physics, Vector Potential, Electromagnetic Heating: A Primer
Ugo Cerchiari

2. Thermometry: Clinical Aspects and Perspectives
Barbara Baiotto and Piergiorgio Marini

3. Physical Background and Technical Realizations of Hyperthermia
Andras Szasz, Oliver Szasz and Nora Szasz

4. Thermotherapy and Nanomedicine: Between Vision and Reality
Andreas Jordan

SECTION II: BIOLOGICAL ASPECTS OF HYPERTHERMIA

5. Influence of Tumor Microenvironment on Thermoresponse:
Biologic and Clinical Implications
Gian Franco Baronzio, Alberto Gramaglia, Attilio Baronzio and Isabel Freitas

6. Hyperthermia and Angiogenesis: Results and Perspectives
Cristina Roca and Luca Primo

7. Vascular Effects of Localized Hyperthermia
Debra K. Kelleher and Peter Vaupel

8. On the Biochemical Basis of Tumour Damage by Hyperthermia
Paola Pietrangeli and Bruno Mondovì

9. Results of Hyperthermia Alone with Radiation Therapy and/or Chemotherapy
Pietro Gabriele and Cristina Roca

10. Thermo-Chemo- Radiotherapy Association: Biological Rationale, Preliminary Observations on Its Use on Malignant Brain Tumors
Gian Franco Baronzio, Vincenzo Cerreta, Attilio Baronzio, Isabel Freitas, Marco Mapelli
and Alberto Gramaglia

11. A Step Deep on Hyperthermia, Hypoxia and Chemotherapy Interactions
Giammaria Fiorentini, Ugo De Giorgi, Maurizio Cantore, Andrea Mambrini
and Stefano Guadagni

SECTION III: CLINICAL ASPECTS OF HYPERTHERMIA

12. Locoregional Hyperthermia
E. Dieter Hager

13. Hyperthermia and Radiotherapy in the Management of Prostate Cancer
Sergio Villa

14. Tumor Ablation Using Radiofrequency Energy: Technical Methods
and Application on Liver Tumors
Johannes-Marcus Hänsler, Luigi Solbiati, E. Dieter Hager, Tiziana Ierace, Luca Cova and Gian Franco Baronzio

15. Cytoreduction, Peritonectomy and Hyperthermic Antiblastic Peritoneal Perfusion for the Treatment of Peritoneal Carcinomatosis
Michele De Simone and Marco Vaira

16. Hyperthermic Isolated Limb Perfusion
Michele De Simone and Marco Vaira

17. Intracavitary Hyperthermic Perfusion
E. Dieter Hager

18. Whole Body Hyperthermia at 43.5-44^oC: Dreams or Reality?
Alexey V. Suvernev, Georgy V. Ivanov, Anatoly V. Efremov and Roman Tchervov

19. Extreme Whole-Body Hyperthermia with Water-Filtered Infrared-A Radiation
Alexander von Ardenne and Holger Wehner

20. Effects of Local and Whole Body Hyperthermia on Immunity
Gian Franco Baronzio, Roberta Della Seta, Mario D’Amico, Attilio Baronzio, Isabel Freitas, Giorgio Forzenigo, Alberto Gramaglia and E. Dieter Hager

21. Fever, Pyrogens and Cancer
Ralf Kleef and E. Dieter Hager

22. Future Perspectives of Interstitial and Perfusional Hyperthermia
Gian Franco Baronzio, Michele De Simone, Gianmaria Fiorentini, Salvatore D’Angelo, Giovanni Visconti and E. Dieter Hager

Addendum: Radiofrequency Thermal Ablation in the Treatment of Lung Malignancies
Cosimo Gadaleta, Anna Catino and Vittorio Mattioli